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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKDC
All Species:
15.76
Human Site:
Y3378
Identified Species:
38.52
UniProt:
P78527
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78527
NP_001075109.1
4128
469089
Y3378
E
K
V
I
A
G
L
Y
Q
R
A
F
Q
H
L
Chimpanzee
Pan troglodytes
XP_001147162
4128
468882
Y3378
E
K
V
I
A
G
L
Y
Q
R
A
F
Q
H
L
Rhesus Macaque
Macaca mulatta
XP_001100610
4128
469402
Y3378
E
K
V
I
A
G
L
Y
Q
R
A
F
Q
H
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P97313
4128
471369
Y3378
E
T
V
I
T
G
L
Y
Q
R
A
F
H
H
L
Rat
Rattus norvegicus
NP_001101797
2098
241314
M1409
L
Y
A
K
R
G
L
M
E
Q
K
L
E
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514950
4153
474137
H3403
Q
K
V
I
A
G
L
H
R
R
A
F
Q
Y
L
Chicken
Gallus gallus
Q8QGX4
4134
472639
N3384
E
K
I
L
A
G
L
N
K
R
A
F
Q
C
F
Frog
Xenopus laevis
Q9DEI1
4146
473487
Y3395
E
N
V
V
G
G
L
Y
R
K
S
L
H
Y
F
Zebra Danio
Brachydanio rerio
XP_001919588
4119
467204
Q3374
A
Q
V
V
E
G
L
Q
I
Q
A
L
E
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781813
1817
205237
K1128
H
S
L
S
S
S
A
K
R
E
E
Q
S
M
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.5
N.A.
N.A.
79.1
39.2
N.A.
74.1
68.8
64
58.5
N.A.
N.A.
N.A.
N.A.
20.8
Protein Similarity:
100
99.8
98.8
N.A.
N.A.
88.7
44.7
N.A.
85.4
82.5
79.8
76.1
N.A.
N.A.
N.A.
N.A.
31.6
P-Site Identity:
100
100
100
N.A.
N.A.
80
13.3
N.A.
73.3
60
33.3
33.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
N.A.
N.A.
80
33.3
N.A.
100
80
66.6
60
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
50
0
10
0
0
0
70
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
60
0
0
0
10
0
0
0
10
10
10
0
20
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
60
0
0
20
% F
% Gly:
0
0
0
0
10
90
0
0
0
0
0
0
0
0
0
% G
% His:
10
0
0
0
0
0
0
10
0
0
0
0
20
40
0
% H
% Ile:
0
0
10
50
0
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
0
50
0
10
0
0
0
10
10
10
10
0
0
10
0
% K
% Leu:
10
0
10
10
0
0
90
0
0
0
0
30
0
10
60
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% M
% Asn:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
10
0
0
0
0
0
10
40
20
0
10
50
0
0
% Q
% Arg:
0
0
0
0
10
0
0
0
30
60
0
0
0
0
0
% R
% Ser:
0
10
0
10
10
10
0
0
0
0
10
0
10
0
0
% S
% Thr:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
70
20
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
50
0
0
0
0
0
20
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _